• HugeNerd@lemmy.ca
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    4 hours ago

    Our medical knowledge is shockingly rudimentary. Why we can’t coax cells to do what they did anyway before is something we really need to understand to pretend to have any kind of medical knowledge. What passes for medicine is nothing more than 19th century++. See this, do that, body will heal. That’s about it. I’m shocked every time I see someone in a wheelchair, how can we have LLMs and hallucinated movies but not understand how a few milligrams of organic matter organizes into nerves? etc etc etc

    I am hoping that the absolutely bonkers computing power we are currently wasting on fart videos will be used to simulate matter in the future, here’s to cheering on the AI crash!

    • Soggy@lemmy.world
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      2 hours ago

      We have a pretty good idea how things work during development, it’s tricking those cells into the same process as a fully-formed organism that’s hard. Isolating and distributing the hormones in the right way. I think you’re underselling the complexity and scale of biology. We can’t just put a tiny camera and chemo-sensor inside a neuron and see what’s going on in real time and synthesize up a hundred thousand copies.

  • FrostyTheDoo@lemmy.world
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    7 hours ago

    I no longer get excited about medical innovation because I know I’ll never be able to afford to benefit from any of it. I’m lucky to have gotten vaccinated as a child while that was still legal for the poors

  • wabafee@lemmy.world
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    6 hours ago

    I bet the catch here is it could accidentally grow anywhere in the body as long as it mimics what our mouth has (saliva). Imagine growing enamel in our tongues or throat.

  • ZILtoid1991@lemmy.world
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    16 hours ago

    How long until the dental restoration industry lobbies it out to be banned, so they can keep selling their photoshop jobs of people smiling with new teeth alongside crowns and implants, all at an inflated price?

    • Wispy2891@lemmy.world
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      16 hours ago

      It already happens with nano-hydroxyapatite pastes. In Europe you find them at the supermarket for 5 euro, in USA you need a prescription and it’s sold for $$$

      • Axum@lemmy.blahaj.zone
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        11 hours ago

        Uh no. You can get nHA toothpaste in the USA without a prescription, not sure why you’d think that. It’s just not a popular item here so it’s not sold at brick and mortar stores for the most part, though some smaller stores have it. But I have no problem ordering the stuff online.

        Edit: Target apparently carries one brand now

        • Soggy@lemmy.world
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          2 hours ago

          Proudly “fluoride free” too, which makes me immediately doubt the veracity of their dental health claims.

  • MIDItheKID@lemmy.world
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    19 hours ago

    Hell yeah. I’m gonna overuse this shit and just have 2 gigantic teeth. One on the top and one on the bottom. No more flossing for me. Fuse those bad boys together. I’ll have the smile of an N64 game character.

  • Tollana1234567@lemmy.today
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    13 hours ago

    isnt that why naHp DOES already in a dental setting/implant, but there hasnt been definitive studies where its conclusive with OTC usage, eventhough there are tons of nahp products out there already from 5-10% with extremely questionable concentration and efficacy as manufactors, often from asia, dont tell thier process of making the toothpastes, and the true concentrations(Davids hide thier ingredients and process so be warned, also it tends to be highly abrasive). i have used some, i noticed most of them are just whitening toothpaste(hence the placebo effect), or overly saturated mint.

  • mastertigurius@lemmy.world
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    1 day ago

    “Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life against physical, chemical, and thermal insults,” said lead author Dr. Abshar Hasan

    This man doesn’t just disapprove of people mistreating their teeth, he is personally insulted by it. A true dentist.

    • Deconceptualist@leminal.space
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      1 day ago

      I could never ever work in that field, it gives me the ick. So I appreciate people who can.

      Also enamel is the hardest substance in your body; AFAIK chemically it is indeed interesting and hard (ha) to emulate with other bio-safe materials.

      • 7U5K3N@lemmy.dbzer0.com
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        22 hours ago

        I could never ever work in that field, it gives me the ick. So I appreciate people who can.

        It’s almost as bad being married to someone that works in that field.

        My wife is a dental hygienist. Some of the horrific shit she sends me would turn your stomach. And then the experiences she’s had working on teeth… Just so so gross. 🤮🤮

        • b34k@lemmy.world
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          20 hours ago

          My wife is also a dental hygienist, and she has never once sent me any horrific shit…. So I don’t think that’s a trait necessarily tied to the occupation, lol

          • 7U5K3N@lemmy.dbzer0.com
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            21 hours ago

            Got a photo one time when we were dating… was hoping for tits. Nope tooth root and all. It fell out when she cleaned the years of solidified shit off it.

            Granted she was in public health in a poor poor poor community but still. Gross.

            • burntbacon@discuss.tchncs.de
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              15 hours ago

              Oh, man, that reminds me of one time when I cracked a tooth and couldn’t get in to see the dentist for a while. Cleaning the whatever out of the inside was so gross in smell, taste, and feeeeel, and so incredibly painful.

      • Ŝan@piefed.zip
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        1 day ago

        But will it allow us to create new body armors, is what I want to know.

        • 474D@lemmy.world
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          1 day ago

          Simply line yourself with the teeth of your enemies (if they flossed regularly)

          • Ŝan@piefed.zip
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            22 hours ago

            Hmmm maybe þe stench of þe rotting teeþ of your enemies who had poor dental hygiene would be a more effective deterrent?

            If þey didn’t have poor hygiene, why were þey your enemies?

        • Mac@mander.xyz
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          17 hours ago

          Hard is usually opposed to strong. It doesn’t take much force to break a tooth—ive done it!

  • AmidFuror@fedia.io
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    1 day ago

    The researchers used extracted human molars as an ex vivo model, first etching their enamel or dentine surfaces with acid to mimic different stages of tooth erosion. They then applied a single coating of the biomimetic elastin-like recombinamer (ELR) gel and let it dry. Finally, the teeth were immersed in carefully controlled mineralization baths that replicated the ionic environment of saliva.

    Keep in mind this hasn’t been shown to actually help teeth in someone’s mouth.

    • Gigasser@lemmy.world
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      15 hours ago

      My guess is that they can slowly regrow lost enamel under fillings, slowly build back up later by layer until a filling is no longer needed. What would be amazing is a cure for gum disease.

      • mastertigurius@lemmy.world
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        14 hours ago

        To be fair, the research is on regenerating, not regrowing. I wouldn’t expect regrowing lost teeth to be possible any time soon, unless some kind of bio 3D-printing method became available.

        • deathbird@mander.xyz
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          16 hours ago

          I definitely saw lots of ads on AliExpress for gels that would regrow your teeth before their algorithm realized I wasn’t there for that.

  • Simulation6@sopuli.xyz
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    22 hours ago

    Can they make one to generate beaver enamel? I will accept the red color if I can chew through a tree.

    • Tollana1234567@lemmy.today
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      13 hours ago

      beaver have a different composition, its made of iron compounds, i dont think human mouths are adapted to have iron teeth, it might damage your other teeth, because iron is much harder than calcium hydroxyapatite.

    • BeeegScaaawyCripple@lemmy.world
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      14 hours ago

      there are times i think about getting titanium caps, but my one crown does not feel great and i don’t like how mouthpieces feel