I think you can do it, but some people will struggle. As others have already mentioned, humans are social animals. Many studies conclude that social connection is one of the biggest factors that boosts well-being (https://hsph.harvard.edu/news/the-importance-of-connections-ways-to-live-a-longer-healthier-life/), this doesn’t necessarily mean that you should marry someone and become a social butterfly, it just means that you should avoid isolation for long periods of time.