In our latest attempts to make lab rats immortal, a new compound has been shown to reverse late stage Alzheimer’s disease in lab mice. This is a rare case where the title isn’t even clickbait.

  • Honytawk@feddit.nl
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    13 minutes ago

    Where is that comic about reporters creating misinformed headlines about science?

  • gibmiser@lemmy.world
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    18 hours ago

    In a mouse model. The mice don’t have alzheimers they have… something we gave them that looks like it… Hopefully it is similar enough

    • Dr. Bob@lemmy.ca
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      18 hours ago

      We did something to the mice then rescued it in a different way. Hooray! Next we’ll save test tubes from cancer…again.

      • scarabic@lemmy.world
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        15 hours ago

        If you can’t get excited by incremental advancements, you should probably unsubscribe from science as a topic.

        • Dr. Bob@lemmy.ca
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          10 hours ago

          Dude it’s worse than that. I was a working neuroscientist for almost twenty years. So…jaded.

    • SaveTheTuaHawk@lemmy.ca
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      16 hours ago

      There has been a fucking epidemic of MD/scientists running to the media with miracle cures lately.

      Mice to not get Alzheimers, they were engineered to show one aspect of the disease that has been promoted by fraudulent studies. As for the reversal, mouse brains are highly plastic and similar to a human baby, nothing like a >60 year old.

    • piconaut@lemmy.ca
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      17 hours ago

      Yeah, I didn’t read the whole thing but apparently only in 5xFAD mice. I wish they would have also tried it in a Tau model like PS19.

  • bizarroland@lemmy.world
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    17 hours ago

    Mouse grandpa: John?

    Mouse Grandson: Grampa, you remember me?

    Mouse grandpa: Yes, I remember. It’s all coming back now. You ate my cheese and fucked my wife you piece of shit!

    Sounds of mouse battle reverberating

  • MinnesotaGoddam@lemmy.world
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    11 hours ago

    it’s lab mice. it’s NAD+. i can’t remember because i’m not an ad researcher, but there are 3 models of AD. one is NAD+, two aren’t. Most of the research was going into NAD+ or another, and they discovered that that specific model was not going to help human patients. It did nothing to effect research or funding. that was about… 15 years ago? so forgive me if i don’t get up.

  • KneeTitts@lemmy.world
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    15 hours ago

    I believe this population of super-mice we are making that are immune to all disease will be the dominant life form on earth after we have extincted ourselves. Im in favor of this future.

    • hector@lemmy.today
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      4 hours ago

      Any drug would cost 20 million a course. Not even exagerating there either. A new one is doing dynamic pricing, charging some as much as 3 million and others over 1 million for a course. For drugs developed with goddamned charity money.

      • InabaResident@feddit.org
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        9 hours ago

        While often true, they still end up making life better for millions of people often enough to be worth it.

  • PushButton@lemmy.world
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    16 hours ago

    Aahh, those lucky mice. Yet another cure for Alzheimer, without counting the multiple cancer miracle-like cures.

    Any news for human yet?

  • the_q@lemmy.zip
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    16 hours ago

    I hate how we treat animals for the benefit of an objectively worse animal.

    • Communist@lemmy.frozeninferno.xyz
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      5 hours ago

      Curing disease is undoubtedly worth animal suffering. Once the disease is cured the benefits will confer to all future humans until we go extinct, I am certain if you were suffering from alzheimers you’d be of a different opinion.

      point these criticisms at the cosmetics industry.

      • hector@lemmy.today
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        4 hours ago

        You are not including the US in humanity clearly, because few can afford this kind of drug here.

        • boonhet@sopuli.xyz
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          48 minutes ago

          Yea but the rest of us will still benefit. The US is like 5% of the world’s population, give or take. Okay there’s other countries with shitty health care systems (developing ones where they just haven’t gotten there yet), but I’d reckon like 80% of the world’s population would have easy and cheap or free access to it through government funded healthcare, or at least a better private system than the US. That’s still a net good. Y’all just need to get your shit in order, but unfortunately at this point it’s going to be harder and harder to do it without violence.

        • Communist@lemmy.frozeninferno.xyz
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          2 hours ago

          The existence of such a drug benefits humanity even if the USes barbaric policies prevent adoption.

          furthermore even if nobody in the US got it ever it would still help an unimaginable number of people

          what is the logic here? Don’t help medicine move along because of one crazy country?

          • hector@lemmy.today
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            2 hours ago

            Advancements are only for the rich in these lands. Far from still being for the benefit, prolonging the rich’s lives is arguably not.

            It would be an advancement if the rights to the drug were owned by some sort of benefit corporation, or non profit, or were not sold to the worst people in the world.

            It’s not though. They are maximizing revenue with no one in government to stop them, to call them on gouging.

    • TheLeadenSea@sh.itjust.works
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      13 hours ago

      All value judgements are subjective. “Better” and “worse” are value judgements, not statements about reality, so they cannot be objective. But subjectively I agree with you that we treat animals awfully, not even mainly in science experiments - at least they have a tangible benefit. Just look at the way animals are bred to be tortured and murdered in factory farms.