Following on from their breakthrough human trial that successfully reprogrammed the immune system to overpower glioblastoma, an aggressive brain tumor, the same scientists have now further developed the mRNA vaccine to fight not one but any cancer. It has the potential to do away with chemotherapy,…
  • Grandwolf319@sh.itjust.worksEnglish
    46·
    4 days ago

    While the formulation isn’t unlike the Covid-19 vaccine, which uses lipid nanoparticles to deliver the genetic instructions to the body, it is still somewhat different. Instead of the drug encoding a virus protein, it sends a message to the immune system to rally the troops. It essentially tells the body to produce certain proteins that stimulate the immune system – including a protein within cancer cells known as PD-L1 (Programmed Death-Ligand 1), which makes tumors become more visible to immune cells.

    TLDR: they are finding that it’s more effective to make cancer more visible and have the body’s immune system do its thing.