I’m not looking for medical advice, but more understanding. I have chronic back pain. I can alleviate it completely with only 2 things - alcohol and a heating pad. Ibuprofen lessens it but it’s still present. Muscle relaxers do nothing (which makes sense because it’s not muscle related, it’s spinal disk degeneration).
A tall glass of whiskey makes my back relax and I can move normally. Once it wears off tho, it’s right back to tense and painful.
Everybody is different.
I can’t metabolize most painkillers, they do literally nothing to me because I’m missing a liver enzyme. I could eat a handful of percacet every day for months and quit cold turkey easy, because I was never really getting anything out of to begin with.
There are countless reasons why people react differently to medication, that’s why doctors just try random shit till something seems to work.
It might be educated guesswork, but it’s still guesswork. And there’s very little effort put into why/how one thing worked over others, if it works that’s the end of it.