There is this dystopia anime series called From the New World. The premise is a portion of humanity gained psychic power and led to the collapse of society because it’s so powerful that order could not be enforced. Far into the future there’s a cluster of communities that’s able to exist, and the way they went about it was to genetically engineered humans so when they harm another human it triggers body functions that make it harder for them to breath and other things. Killing another human also kills the aggressor. It kind of works on the interpretative level so it’s possible that using drones could still have an effect, probably.

Even in the story they explored ways to circumvent it though, but that’s kind of a tangent.