So, I assume that if you put 100 people on a spaceship and sent them to wherever, they’d get very inbred in a few generations. How many people would you need for this to not happen, accounting for the fact that there will eventually be people who are infertile or die before having children?
Not what you mean, but one woman and a shit-ton of frozen sperm and ova would probably work, say 3 for redundancy…